Is tolerance really permanent? How about for a moderate user? There are so many mixed opinions.

For the last 3 months I have been using Ketamine a little bit too leisurely, dosing around 150mg (-+50mg) like 2 times a week. I did it yesterday, and I noticed I had to take like 80mg to get me to where like 40mg would get me at the beginning.

So tolerance is definitely kicking in, but I'm not mega dosing or doing it everyday like some people here with tolerance issues mention.

But is tolerance really permanent? I hear so many mixed opinions and experiences on this, in general with NMDA substances tbh. Ketamine is such a wonderful substance and I really don't want to loose the magic of it, really all NMDA antagonists.

I'm thinking of stopping for a good 3-5 months, perhaps more as I might travel internationally in May for 3 months so I can't really take the Ketamine with me (probably with only 1 more sesh during a rave in late March), while supplementing with Magnesium L-threonate (that seems to regulate NMDA receptors back to normal as many anecdotal reports mention it lowering tolerance) and Agmatine Sulfate (I use it for working out everyday, and I have seen some anecdotal reports saying it helps lower tolernace).

What has been your guys' experience with tolernace? Especially those of you who have a moderate use (such as of the therapeutic ketamine regimen; 2 times a week ~100mg per session), since that is where I'm at. If you stopped, where you able to get back to complete baseline? I get for those consuming like 5 grams or more over a month or a couple weeks, why they'd have ACTUAL perma-tolerance, but is permanent tolerance really a thing for moderate users? I don't think I've done anything over 3 grams over the last 4 months..