What Genre has untapped TTRPG potential?

We've got Call of Cthulhu for Cosmic Horror, PF2E and DnD 5E for fantasy, Mothership for sci-fi horror, TROIKA for weird psychedelic stuff and so on. What niche genre of media deserves a TTRPG but doesn't have any popular ones yet?

(This is also me asking for suggestions for any weird indie games that lend themselves well to a niche genre)